GlucoMend is a synergistic herbal formula that has been designed to help maintain healthy blood sugar levels, and is ideal for individuals with insulin and glucose-related conditions such as metabolic syndrome and diabetes.
GlucoMend contains standardized compounds, which include: corosolic acid from Banaba, isoflavones from Kudzu, ginsenosides from American Ginseng, saponins from Fenugreek, gymnemic acid from Gymnema. These standardized compounds all work together to slow glucose absorption and regulation insulin. Other ingredients include berberine, a compound known for improving blood glucose regulation and insulin sensitivity, fenugreek7-10 which has a long history of use in Indian in Chinese medicine for slowing the absorption of glucose, and Cinnamomum cassia extract for its chromium and polyphenol content. These compounds can:
improve insulin-regulated glucose utilization, enhance insulin signaling in the skeletal muscle, and aid glucose to glycogen conversionWho Should Take GlucoMend?
Those who would benefit from proactively maintaining optimal blood sugar and those with dysglycemic conditions including metabolic syndrome, diabetes and polycystic ovary syndrome. GlucoMend may be helpful for patients needing to lose weight and/or control lipids.Who Should Not Take GlucoMend?
This product should not be taken by pregnant or nursing women or by patients with known allergies to any of the herbs found in this formula.
Caution: This product should only be used under the supervision of a qualified health care practitioner who can actively monitor a patient’s blood sugar levels if they are diabetic and/or are using blood sugar modulating medication or insulin.How Do I Take GlucoMend?
As a dietary supplement, take four capsules per day with meals, or as directed by a health care practitioner (divided dosing recommended).
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
- Yin J, Xing H, Ye J. Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism. 2008 May;57(5):712-7.
- Zhang H, Wei J, Xue R, et al. Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression. Metabolism. 2010 Feb;59(2):285-92.
- Liu, L, et al. Berberine suppresses intestinal disaccharidases with beneficial metabolic effects in diabetic states, evidences from in vivo and in vitro study. Naunyn Schmiedebergs Arch Pharmacol. 2010 Apr;381(4):371-81.
- Al-masri IM, Mohammad MK, Tahaa MO. Inhibition of dipeptidyl peptidase IV (DPP IV) is one of the mechanisms explaining the hypoglycemic effect of berberine. J Enzyme Inhib Med Chem. 2009 Oct;24(5):1061-6.
- Yin J, Gao Z, Liu D, Liu Z, Ye J. Berberine Improves Glucose Metabolism through Induction of Glycolysis. American journal of physiology Endocrinology and metabolism. 2008;294(1):E148-E156.
- Turner N, Li JY, Gosby A, et al. Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action. Diabetes. 2008 May;57(5):1414-8.
- Raghuram TC, Sharma RD, Sivakumar B, and et al. Effect of fenugreek seeds on intravenous glucose disposition in non-insulin dependent diabetic patients. Phytotherapy Research 1994;8(2):83- 86.
- Bordia, A., Verma, S. K., and Srivastava, K. C. Effect of ginger (Zingiber officinale Rosc.) and fenugreek (Trigonella foenumgraecum L.) on blood lipids, blood sugar and platelet aggregation in patients with coronary artery disease. Prostaglandins Leukot Essent Fatty Acids 1997;56(5):379-384.
- Sharma RD and Raghuram TC. Hypoglycaemic effect of fenugreek seeds in non-insulin dependent diabetic subjects. Nutr Res 1990;10:731-739.
- Sharma RD, Raghuram TC, and Rao NS. Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes. Eur J Clin Nutrit 1990;44(4):301-306.
- Milot, B. and Blumenthal, M. Asian and American Ginsengs Act Differently on Acute Glycemia. HerbalGram 2004;(64):24.
- Blumenthal, M., Busse, W., Goldberg, A., and et al. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. 1998;90.
- World Health Organization. WHO Monographs on Selected Medicinal Plants. 1999;1:168.
- Baskaran, K, Ahamath, BK, Shanmugasundaram, KR, and et all. Antidiabetic effect of a leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients. J Ethnopharm 1990;30:295-305.
- Cicero, AF, Derosa, G, and Gaddi, A. What do herbalists suggest to diabetic patients in order to improve glycemic control? Evaluation of scientific evidence and potential risks. Acta Diabetol. 2004;41(3):91-98.
- Grover, JK, Yadav, S, and Vats, V. Medicinal plants of India with anti-diabetic potential. J Ethnopharmacol. 2002;81(1):81-100.
- Bishayee, A and Chatterjee, M. Hypolipidaemic and antiatherosclerotic effects of oral gymnema sylvestre R. Br. leaf extract in albino rats fed a high fat diet. Phytother Res 1994;8:118-120.
- Murakami, C, Myoga, K, Kasai, R, Ohtani, K, Kurokawa, T, Ishibashi, S, Dayrit, F, Padolina, WG, and Yamasaki, K. Screening of plant constituents for effect on glucose transport activity in Ehrlich ascites tumour cells. Chem Pharm Bull.(Tokyo) 1993;41(12):2129-2131.
- Judy, WV, Hari, SP, Stogsdill, WW, Judy, JS, Naguib, YM, and Passwater, R. Antidiabetic activity of a standardized extract (Glucosol) from Lagerstroemia speciosa leaves in Type II diabetics. A dose-dependence study. J Ethnopharmacol. 2003;87(1):115-117
- Shi, WG, Qu, L, and Wang, JW. [Study on interventing effect of puerarin on insulin resistance in patients with coronary heart disease]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 2002;22(1):21-24.
- Khan, A, Safdar, M, Ali Khan, MM, Khattak, KN, and Anderson, RA. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003;26(12):3215-3218.
- Choi, J, Lee, KT, Ka, H, Jung, WT, Jung, HJ, and Park, HJ. Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. Arch Pharm
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